产品货号：
GS4517
中文名称：
重组人MIP-1α/CCL3
英文名称：
Recombinant Human Macrophage Inflammatory Protein-1 alpha/CCL3
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 7.8kDaprotein containing 70 amino acid residues,including the four highly conserved cysteine residues present in CC chemokines.
储存条件：冷冻（-20℃）
概述
CCL3,also known as macrophage inflammatory protein-1α(MIP-1α),is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.Studies showed CCL3 can bind to CCR1,CCR4 and CCR5.MIP-1α can induce a dose-dependent inhibition of different strains of HIV-1,HIV-2,and simian immunodeficiency virus(SIV).Recombinant human MIP-1α is a 7.8kDaprotein containing 69 amino acid residues,including the four highly conserved cysteine residues present in CC chemokines and it shares approximately 73%,74%and 92%amino acid sequence homology with the murine,rat and rhesus macaque protein.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人MIP-1α/CCL3，MIP-1α/CCL3, Human
储存条件：冷冻（-20℃）
概述
CCL3,also known as macrophage inflammatory protein-1α(MIP-1α),is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.Studies showed CCL3 can bind to CCR1,CCR4 and CCR5.MIP-1α can induce a dose-dependent inhibition of different strains of HIV-1,HIV-2,and simian immunodeficiency virus(SIV).Recombinant human MIP-1α is a 7.8kDaprotein containing 69 amino acid residues,including the four highly conserved cysteine residues present in CC chemokines and it shares approximately 73%,74%and 92%amino acid sequence homology with the murine,rat and rhesus macaque protein.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞96%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,100 mM NaCl. |
| 内毒素 | Less than 1 EU/ug of rHuMIP-1α/CCL3 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA |
相关搜索：重组人MIP-1α/CCL3，MIP-1α/CCL3, Human